|
KMID : 0359720120300020128
|
|
Journal of the Korean Neurological Association
2012 Volume.30 No. 2 p.128 ~ p.131
|
|
|
An Autopsy Case of Amyotrophic Lateral Sclerosis with Neuroinflammatory change
|
|
Ha Seung-Hyun
Paek Won-Ki
Kim Hyun-Young
Noh Min-Young
Hwang Se-Jin
Kim Seung-Hyun
|
|
|
Abstract
|
|
|
|
Neuroinflammation such as reactive gliosis and microglial activations are important pathological findings of ALS. We present a first autopsy case of ALS in Korea related with neuroinflammatory change. A 67-year-old ALS patient suddenly expired due to accidental head trauma. Gross autopsy finding showed marked atrophic change in spinal cord. Pathological finding include a marked loss of motor neurons, reactive gliosis and microglial infiltrations. These findings suggest neuroinflammation may play a role in pathogenesis of ALS.
|
|
|
KEYWORD
|
|
|
Amyotrophic lateral sclerosis, Autopsy, Neuroinfla
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
  
|